People with Stargardt disease may have yellowish flecks in and under the macula that sometimes extend outward in a ring-like fashion. The flecks are deposit of lipofuscin, a fatty byproduct of normal cell activity. Liposfuscin builds up abnormally in patients with Stargardt disease.
Patients with Best’s disease have a yellow cyst that forms under the macula. The cyst eventually ruptures, spreading fluid and yellow deposits, which may harm the macula.
In patients with juvenile retinoschisis, the retina splits into two layers affecting the macula. The spaces between the layers can be filled with blisters, and blood vessels can leak into the vitreous, the fluid filling the eye. Juvenile retinoschisis can lead to retinal detachments.
Your Eye M.D. may perform a fluorescein angiography to confirm the diagnosis. In this test, a dye is injected into the arm, which is then photographed as it circulates through the blood vessels in the retina. Your Eye M.D. may also order an ERG (electroretinography) test, which measures the electrical activity of the retina.
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