Chemotherapy is the use of medication to kill cancer cells. Chemotherapy can be given directly in the eye, through a vein, or directly into the cerebrospinal fluid. If the cancer does not respond to treatment, or if it comes back, the doctor may recommend high-dose chemotherapy followed by a stem cell transplant.

Radiation therapy uses high-energy radiation to shrink tumors and kill cancer cells. For treating lymphoma of the eye, it may be directed only at the affected eye or at both eyes, depending upon where the cancer is. Radiation therapy may also be directed to the brain and spinal cord to help prevent the cancer from spreading there or to help destroy undetected cancer cells that could be there.

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