Anisocoria is usually a condition that has no effect on the overall health of your eyes. This type is called physiologic anisocoria, and is a common condition, with as many as one in five people having some degree of difference in the size of their pupils. However, anisocoria can also be a symptom of a serious eye disorder, including third nerve cranial nerve palsy and Horner’s syndrome. Both are nervous system disorders that can occur when nerves that travel to the eye are damaged by a stroke, tumor or trauma. Anisocoria can also result from a viral infection, syphilis, surgical damage, and or another condition affecting the pupil called Adie’s tonic pupil.

Image courtesy of Steven A. Newman, MD.

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