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Why was beta carotene omitted from Bausch & Lomb's AREDS-2 formulation?

The change in the AREDS formulation (nutritional supplements used to slow the progress of age-related macular degeneration, or AMD) results from the AREDS2 trial, where former smokers who took the formulation with beta-carotene had a higher incidence of lung cancer. This was not the case when taking the formulation with lutein/zeaxanthin. Also, participants who took a formulation with lutein/zeaxanthin and no beta-carotene had a slightly lower risk of progressing to advanced AMD when compared to those who took the previous formulation with beta-carotene and no lutein/zeaxanthin.

Answered by: Paul Sternberg Jr., MD Dr. Paul Sternberg

Categories: Eye Diseases

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Answered: Jul 28, 2014

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