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Could a niacin flush have an effect on the pigments in the iris causing a discoloration that results in lightening or darkening the eyes?

No. The iris has but one pigment—melanin. Iris color is determined by the density of the melanin in the layers of the iris. Niacin would not affect that. If you believe that you have a discoloration or change in color of your iris—check with your ophthalmologist. There are conditions that can cause such change and these changes should be investigated.

Answered by: Ivan Schwab, MD Dr. Ivan Schwab

Categories: Eye Conditions

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Answered: Feb 07, 2013

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